High-throughput screening (HTS) laboratories are the backbone of drug discovery, biotechnology, and life sciences research. These labs process thousands—if not millions—of samples using automation, microplates, and disposable plastics like pipette tips. While these technologies drive efficiency, they also generate significant waste.

Sustainability is becoming a top priority for research institutions, pharmaceutical companies, and biotech firms alike. Implementing circular economy practices in HTS labs can reduce costs, minimize environmental impact, and contribute to corporate sustainability goals. Here’s how lab managers, researchers, and procurement teams can advocate for and implement greener practices in high-throughput screening environments.

1. Reuse Over Replace: The Power of Circularity

Many High-Throughput Screening labs rely on single-use plastics for convenience and sterility, but reusing consumables can significantly reduce costs and waste.

• Microplate Cleaning & Reuse: Advanced cleaning technologies like IonField System’s PurePLATE MCS allow for microplates to be decontaminated and reused multiple times without compromising assay integrity. Investing in automated microplate cleaning systems can dramatically reduce procurement expenses and landfill waste.
• Pipette Tip Reuse: While traditionally considered single-use, Ionfield System’s PureTIP Liquid Handler Companion now makes pipette tip reuse a reality, eliminating residual contamination and extending the life of expensive consumables.

2. Sustainable Procurement: Making Smarter Choices

Lab managers should consider sustainability when purchasing consumables and equipment.

• Eco-Friendly Alternatives: Look for manufacturers that offer biodegradable plastics, recycled content, or alternative materials.
• Vendor Partnerships: Collaborate with suppliers who prioritize sustainability and offer take-back programs for used consumables.
• Energy-Efficient Equipment: Automation platforms with energy-saving modes and reduced standby power consumption can lower the lab’s carbon footprint.

3. Waste Reduction & Recycling Programs

High-Throughput Screening labs should implement structured recycling and waste reduction initiatives:

• Segregate Waste Streams: Differentiate between biohazard, chemical, and recyclable waste to ensure proper disposal and minimize landfill contribution.
• Implement Recycling Stations: Work with waste management vendors to establish recycling for plastic consumables, where feasible.
• Encourage Green Lab Certifications: Programs like My Green Lab’s ACT Label can guide labs in making sustainable purchasing decisions.

4. Engage and Advocate for Change

Creating a sustainable HTS lab requires a cultural shift. Lab personnel can advocate for greener practices by:

• Educating Team Members: Conduct sustainability workshops and training to encourage eco-friendly habits.
• Forming a Green Committee: Establish a group dedicated to sustainability initiatives, providing a platform for ideas and accountability.
• Tracking and Reporting Impact: Regularly measuring waste reduction, cost savings, and environmental impact can reinforce the value of sustainability efforts.

Conclusion

Sustainability and high-throughput screening are not mutually exclusive. By embracing reusable consumables, making smarter procurement decisions, implementing recycling programs, conserving energy, and fostering a culture of sustainability, HTS labs can operate efficiently while reducing their environmental impact. The shift towards sustainable practices is not just beneficial for the planet—it’s a smart business decision that can cut costs, improve brand reputation, and align with global sustainability goals.

By advocating for and implementing these strategies, HTS labs can be at the forefront of a greener, more responsible future for scientific research.